Patients see the price before they leave
Real-time benefit and lower-cost alternatives surface at the point of prescribing — so sticker shock never sends a script to the shelf.
E-prescribing your practice — and your partners — can trust.
A single Surescripts-certified platform that handles EPCS, real-time benefit and formulary checks, and advanced AI capabilities.
HIPAA Compliant
EPCS Ready
19+ Years
Trusted by practices & health-tech partners nationwide
EHR / EMR partner
Health system
Telehealth platform
Multi-site practice
Pharmacy network
Digital health brand
19+
Years in Market
100s of Millions
e-Prescriptions sent
50
States covered
99.95%
Platform uptime
Up to 70%
Prescriptions Supported
Trusted by physicians across the USA for 19+ years — one of the earliest adopters of standalone e-prescribing.
The last mile of prescribing is broken
Scripts stall between the exam room and the pharmacy
Abandoned prescriptions, pharmacy transfers, and callback ping-pong cost practices time and patients their medications. H2H closes the gap at the point of prescribing.
Route to the right pharmacy the first time
Patients pick their own pharmacy up front, and switching is just as easy if plans change — so far fewer calls get rerouted or transferred elsewhere.
Resolve fill issues without clinical staff
Cancels, Rx changes, and refill authorizations happen electronically — no phone tag between the front desk and the pharmacy.
Key Features
Built for Healthcare, Proven in Practice
Everything a prescriber needs to write, check, and manage a script — in one workflow.
Rx
New Rx
Create and send first-time prescriptions in seconds, routed straight to the patient’s pharmacy of choice.
→EPCS
EPCS
Prescribe controlled substances electronically with simplified MFA, fully compliant with 21 CFR Part 1311.
→ePA
Electronic Prior Authorization
Get patients on cost-effective, clinically appropriate medications faster, without the phone tag.
→RFL
Refill Rx
Authorize refills up front so patients can renew a valid prescription without another office visit.
→RxC
Cancel Rx & Rx Change
Cancel a prescription or swap medications instantly when a pharmacy can’t fill it as written.
→AI
AI Prescription Agent
Type or speak the instruction and the agent handles the rest — drafting and validating the prescription automatically, cutting the time providers spend writing scripts by up to 75%.
→RTPB
Real-Time Prescription Benefit
See patient-specific benefit and cost information before the script is sent, not after.
→RTF
Real-Time Formulary
Formulary status, payer alternatives, and co-pay details at the exact point of prescribing.
→Hx
Medication History
Full medication history with drug-drug, drug-allergy, and drug-food interaction checks.
→PDMP
PDMP
Check prescription drug monitoring program data right inside the prescribing workflow, with every lookup captured in a complete audit trail.
→
AI, Built In
Three ways AI speeds up prescribing — with a human in the loop
Our agents draft fast and safely; the provider always reviews and confirms before anything is sent.
T2Rx
Transcribe to Prescribe
Turn a visit transcript into a ready-to-sign prescription. The AI drafts; you confirm.
Learn more →Agent
PrescribeAgent
Instruct by chat or voice in plain language. It drafts and validates; you confirm and send.
Learn more →AI
AI Medication Adherence
Predicts a patient’s likelihood of adhering to a medication before you prescribe it — and surfaces the likely reason when that likelihood is low.
Learn more →
AI, Built In
Three ways AI speeds up prescribing with a human in the loop
Our agents draft fast and safely; the provider always reviews and confirms before anything is sent.
AI
AI Medication Adherence
Predict adherence risk before the script is sent, with reasons you can act on.
Learn more →T2P
Transcribe to Prescribe
Turn clinical notes into draft prescriptions for provider review.
Learn more →Agent
PrescribeAgent
Agentic prescribing workflows with a human always in the loop.
Learn more →
New
AI-Powered Medication Adherence Prediction
Before you prescribe, H2H predicts a patient's likelihood of adhering to a medication — and when that likelihood is low, our proprietary AI/ML algorithm surfaces why, from pharmacy deserts to complex prescription regimens, so you can act before the script is ever sent.
Explore AI Adherence →
Now for patients too
Explore the Patient Portal →
A patient portal that guides every script home
The prescription doesn’t end when it’s sent. H2H gives patients a simple portal to find the right pharmacy, track their medications, and save money — so fewer scripts are left behind.
Pharmacy finder
Find in-network pharmacies ranked by distance and cost.
Medication tracker
Patients see active scripts and refill status.
Savings options
Surface lower-cost pharmacy and coupon paths.
Refill requests
Request refills without calling the office.
Pickup guidance
Clear next steps so fewer scripts are abandoned.
Certified & Compliant
Surescripts Gold Certified
HIPAA Compliant
EHNAC P&S Accredited
21 CFR Part 1311 (EPCS)
Integration Models
Three ways to bring H2H into your workflow
Whichever way your practice or platform is set up, H2H fits without disrupting it.
SA
Stand-Alone Access
For prescribers without an EMR, EHR, or MAR system log in directly to send prescriptions at the point of care.
EMR
Embedded EMR / EHR / MAR
H2H opens from a “prescribe” link inside your existing system; authentication happens behind the scenes.
API
Web API (SOAP & REST)
Connect via H2H’s SOAP or REST web services, with webhooks for real-time status updates, to bring e-prescribing functionality directly into your own application.
Testimonials
Trusted by practices for two decades
"I have worked with H2H for over 15years. they have always provided a great product, at a good price, and when support services have been needed they provide great support."
"My overall experience is a 10/10. I have no issues and I am extremely satisfied with Digital RX. [sensitive content hidden] in customer service is wonderful and I know if I ever have an issue I can call or email her and its revolved asap. As you know being a provider, time is everything so that alone is amazing."
See H2H DigitalRx in your workflow
A 45-minute walkthrough, tailored to your practice or platform.
Request a Demo